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Urinary tract infections and antimicrobial susceptibility pattern among female students in a tertiary institution in southwest Nigeria - A cross sectional study
Tinuade Adesola Ajani1, Charles John Elikwu1, Victor Ugochukwu Nwadike1, Babatunde Tayo1, Opeoluwa Akinleye Shonekan1, Celen Chika Okangba1, Chinenye Gloria Anaedobe2, Tunde Ehimen Thompson1, Azubuike Chidiebere Omeonu1, Faluyi Bibitayo1, Mustapha Akanji Ajani3, Nkadinma Florence Nkwogu4, Joseph Emejuru1, Kelechi Okangba1, Obinna Mark Ugwa1, Marvelous Afolabi1, Abisola Atere1, Temidola Kalejaye1, Timothy A Oluwasola5, Olusegun Akintoye Coker1
1 Department of Medical Microbiology, Benjamin Carson College of Health and Medical Sciences, Ilishan-Remo, Ogun State, Nigeria
2 Department of Medical Microbiology, Federal Capital Territory, University of Abuja, Abuja, Nigeria
3 Department of Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria
4 Department of Haematology, Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria
5 Department of Obstetrics and Gynaecology, College of Medicine, University of Ibadan, Ibadan, Nigeria
Correspondence Address:
Dr. Tinuade Adesola Ajani
Department of Medical Microbiology, Ben Carson School of Medicine, Babcock University, Ilishan-Remo, Ogun State
Nigeria
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jcls.jcls_47_19
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Background: Urinary tract infections (UTIs) is a common medical problem that affects all age groups but with significant morbidity in females because of the nature of their anatomy and physiology. This study was aimed to identify the common causative organisms of UTI and their antimicrobial susceptibility pattern among female students in Babcock University. Methods: A cross-sectional study, in which 200 female participants with symptoms of UTI were recruited. Mid-stream urine was collected from them and processed using the standard microbiological procedures. Antimicrobial susceptibility testing was performed on isolates from the samples with significant bacteriuria. Sociodemographic and risk factors were obtained using standard questionnaires, and statistical analysis was performed using SPSS version 23.0. Results: UTIs were confirmed in 14.5% (29/200) participants. Of the pathogens isolated, Escherichia coli was predominant 30.6% (11/36). Most of the pathogens isolated were susceptible to ofloxacin and gentamicin, while ceftriaxone had the least susceptibility (18.2%). The majority of the participants, 165 (82.5%) though symptomatic, did not have bacteriuria. The participants aged 15–20 years were mostly infected [24 (13.4%)]. No significant association was found between the sociodemographic factors and UTI. Conclusion: The prevalence of UTI from this study was 14.5%. E. coli was the predominant bacteria pathogen isolated, and ofloxacin and gentamycin were the most active antibiotics on susceptibility pattern. The majority of the patients though symptomatic, had no pathogens isolated from their urine. Therefore, caution should be applied on the use of antibiotics when managing UTI based on symptoms alone, to prevent antibiotic resistance
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