Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 155
  • Home
  • Print this page
  • Email this page
ORIGINAL RESEARCH REPORT
Year : 2021  |  Volume : 18  |  Issue : 4  |  Page : 186-190

Serum melatonin levels in women with infertility: A case–control study in a Nigerian university hospital


1 Department of Obstetrics and Gynaecology, Lagos University Teaching Hospital, Lagos, Nigeria
2 Department of Obstetrics and Gynaecology, College of Medicine, University of Lagos, Lagos, Nigeria

Correspondence Address:
Dr. Adegbenga Adetona Ajepe
Department of Obstetrics and Gynaecology, Lagos University Teaching Hospital, Idi-Araba, Lagos
Nigeria
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jcls.jcls_67_20

Rights and Permissions

Background: Infertility is a public health issue in Nigeria, an environment of high daily sunlight exposure. This study objective was to assess the serum melatonin levels among infertile women and parous women in Nigeria. Methods: This was a case–control study involving 45 women of reproductive age with infertility and 45 parous women. Four milliliters of blood sample was collected from each of the participants between 1200 and 1600 h after written informed consent was obtained. Enzyme-linked immunosorbent assay technique using melatonin-specific monoclonal antibody was used for processing the samples. Obtained optical density was plotted and read off a standard curve. Data analysis was conducted with the Statistical Package for the Social Sciences version 23. A P < 0.05 was considered statistically significant. Results: The median serum melatonin values for women with infertility (27.86 pg/ml) and women without infertility (28.12 pg/ml) were similar (P = 0.735). Serum melatonin levels had insignificant negative correlation with age (P = 0.564), body mass index (P = 0.232), and daytime napping (P = 0.604). Melatonin levels had a nonstatistically significant positive correlation with duration of sleep (P = 0.789). Conclusion: This study found no significant difference in the serum melatonin levels in infertile and parous women. Melatonin supplementation in infertile women in our environment for the purpose of improving their fertility may not be recommended.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1080    
    Printed42    
    Emailed0    
    PDF Downloaded128    
    Comments [Add]    

Recommend this journal