Journal of Clinical Sciences

CASE REPORT
Year
: 2022  |  Volume : 19  |  Issue : 2  |  Page : 67--70

Pituitary adenoma with gangliocytoma: A rare mixed tumor in the sellar region


Archana Buch, Neha Agarwal, Tushar Kambale, Charusheela Gore 
 Department of Pathology Dr. D.Y. Patil Medical College, Hospital and Research Centre, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra, India

Correspondence Address:
Dr. Tushar Kambale
Department of Pathology, Dr. D.Y. Patil Medical College, Hospital and Research Center, Dr. D.Y. Patil Vidyapeeth, Pimpri, Pune - 411 018, Maharashtra
India

Sellar gangliocytomas are exceedingly rare, well-differentiated, low-grade neoplasms that frequently occur in the presence of a pituitary adenoma (PA). We report a case of a sellar gangliocytoma coexisting with growth hormone (GH) secreting PA. A 43-year-old man was brought to our hospital with right-eye visual disturbances for 2 months, along with headaches, acromegaly, temporal hemianopia in the right eye, and recent onset of Type 2 diabetes mellitus. Endocrinological studies found elevated serum level of GH. A computed tomographic scan showed a mass in the sellar region with suprasellar extension and thus a diagnosis of an expanding pituitary macroadenoma was established. It was removed by transnasal transsphenoidal surgery. On histopathological examination of the resected specimen, diagnosis of mixed gangliocytoma-PA was confirmed as it showed two distinct morphological components of the tumor comprising neoplastic ganglionic cells and adenomatous cells.


How to cite this article:
Buch A, Agarwal N, Kambale T, Gore C. Pituitary adenoma with gangliocytoma: A rare mixed tumor in the sellar region.J Clin Sci 2022;19:67-70


How to cite this URL:
Buch A, Agarwal N, Kambale T, Gore C. Pituitary adenoma with gangliocytoma: A rare mixed tumor in the sellar region. J Clin Sci [serial online] 2022 [cited 2022 Jun 29 ];19:67-70
Available from: https://www.jcsjournal.org/article.asp?issn=2468-6859;year=2022;volume=19;issue=2;spage=67;epage=70;aulast=Buch;type=0